The following are health and medical definitions of terms that appear in the Obesity article. Abdomen: The belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
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Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Absorption: Uptake. In the biomedical sciences, absorption has diverse specific meanings.
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Addiction: A chronic relapsing condition characterized by compulsive drug-seeking and abuse and by long-lasting chemical changes in the brain. Addiction is the same irrespective of whether the drug is alcohol, amphetamines, cocaine, heroin, marijuana, or nicotine. Every addictive substance induces pleasant states or relieves distress. Continued use of the addictive substance induces adaptive changes in the brain that lead to tolerance, physical dependence, uncontrollable craving and, all too often, relapse. Dependence is at such a point that stopping is very difficult and causes severe physical and mental reactions from withdrawal. The risk of addiction is in part inherited. Genetic factors, for example, account for about 40% of the risk of alcoholism. The genetic factors predisposing to addiction are not yet fully understood.
Alcohol: An organic chemical in which one or more hydroxyl (OH) groups are attached to carbon (C) atoms in place of hydrogen (H) atoms. Common alcohols include ethyl alcohol or ethanol (found in alcoholic beverages), methyl alcohol or methanol (can cause blindness) and propyl alcohol or propanol (used as a solvent and antiseptic ). Rubbing alcohol is a mixture of acetone , methyl isobutyl ketone, and ethyl alcohol. In everyday talk, alcohol usually refers to ethanol as, for example, in wine, beer, and liquor. It can cause changes in behavior and be addictive.
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American Medical Association (AMA): The AMA. The AMA's mission statement proclaims:
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Amino acid: One of the 20 building blocks of protein . The sequence of amino acids in a protein and, hence, the function of that protein are determined by the genetic code in the DNA .
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Analysis: A psychology term for processes used to gain understanding of complex emotional or behavioral issues.
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Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Anesthesia: Loss of feeling or awareness. A general anesthetic puts the person to sleep. A local anesthetic causes loss of feeling in a part of the body such as a tooth or an area of skin without affecting consciousness. Regional anesthesia numbs a larger part of the body such as a leg or arm, also without affecting consciousness. The term "conduction anesthesia" encompasses both local and regional anesthetic techniques. Many surgical procedures can be done with conduction anesthesia without significant pain. In many situations, such as a C-section, conduction anesthesia is safer and therefore preferable to general anesthesia. However, there are also many types of surgery in which general anesthesia is clearly appropriate.
Anger: An emotional state that may range in intensity from mild irritation to intense fury and rage. Anger has physical effects including raising the heart rate and blood pressure and the levels of adrenaline and noradrenaline.
Ankle: The ankle joint is complex. It is made up of two joints: the true ankle joint and the subtalar joint:
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Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue. Antihistamines do not stop the formation of histamine nor do they stop the conflict between the IgE and antigen. Therefore, antihistamines do not stop the allergic reaction but protect tissues from some of its effects. Antihistamines frequently cause mouth dryness and sleepiness. Newer "non sedating" antihistamines are generally thought to be somewhat less effective. Antihistamine side effects that very occasionally occur include urine retention in males and fast heart rate.
Apnea: An apnea is a period of time during which breathing stops or is markedly reduced. There are two types of apneas, the more common obstructive sleep apnea and the less common central sleep apnea.
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Artery: A vessel that carries blood high in oxygen content away from the heart to the farthest reaches of the body. Since blood in arteries is usually full of oxygen, the hemoglobin in the red blood cells is oxygenated. The resultant form of hemoglobin (oxyhemoglobin) is what makes arterial blood look bright red.
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Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis. (see osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudogout).
Aspartame: A man-made sweetener with almost no calories used in place of sugar.
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Asthma : A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs ( alveoli ) or the lung tissue (the parenchyma of the lung) itself.
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Atherosclerosis: A process of progressive thickening and hardening of the walls of medium-sized and large arteries as a result of fat deposits on their inner lining.
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Atkins diet: A high- protein , high- fat , low- carbohydrate weight-loss diet popularized by Dr. Robert C. Atkins that allows for unrestricted amounts of meat, cheese and eggs while severely restricting carbohydrates, including sugar, bread, pasta, milk, fruits and vegetables. The Atkins diet is based on the theory that eating carbohydrates stimulates the production of insulin , which in turn leads to hunger, eating, and weight gain. The theory is that people on the Atkins diet experience reduced appetite and their bodies use stored fat for energy versus burning glucose from ingested carbohydrate. Burning fat for energy is supposedly lead to weight loss.
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Balance: A biological system that enables us to know where our bodies are in the environment and to maintain a desired position. Normal balance depends on information from the inner ear, other senses (such as sight and touch) and muscle movement.
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Bariatric: Pertaining to bariatrics, the field of medicine concerned with weight loss.
Bariatric surgery: Surgery on the stomach and/or intestines to help a person with extreme obesity lose weight. Bariatric surgery is an option for people who have a body mass index (BMI) above 40. Surgery is also an option for people with a BMI between 35 and 40 who have health problems like type 2 diabetes or heart disease .
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Baseline: 1. Information gathered at the beginning of a study from which variations found in the study are measured.
2. A known value or quantity with which an unknown is compared when measured or assessed.
3. The initial time point in a clinical trial, just before a participant starts to receive the experimental treatment which is being tested. At this reference point, measurable values such as CD4 count are recorded. Safety and efficacy of a drug are often determined by monitoring changes from the baseline values.
Belly: That part of the body that contains all of the structures between the chest and the pelvis. Also called the abdomen.
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Bioelectric impedance analysis: A seemingly simple method for determining the lean body mass. Abbreviated BIA. There are two methods of the BIA. One involves standing on a special scale with footpads. A harmless amount of electrical current is sent through the body, and then the percentage of body fat is calculated. The other type of BIA involves electrodes usually placed on a wrist and an ankle and on the back of the right hand and on the top of the foot. The change in voltage between electrodes is measured. The person's body fat percentage is then calculated from the results of the BIA.
Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
Blood glucose: The main sugar that the body makes from the food in the diet. Glucose is carried through the bloodstream to provide energy to all cells in the body. Cells cannot use glucose without the help of insulin .
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".
Blood sugar: Blood glucose. See also: High blood sugar; Low blood sugar.
BMI: Body mass index.
BOD POD: A method for determining the lean body mass. The BOD POD is a computerized, egg-shaped chamber. Using the same whole-body measurement principle as underwater weighing, the BOD POD measures a subject's mass and volume, from which their whole-body density is determined. Using these data, body fat and lean muscle mass can then be calculated.
Body mass index: A key index for relating a person's body weight to their height. The body mass index (BMI) is a person's weight in kilograms (kg) divided by their height in meters (m) squared.
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Bone: Bone is the substance that forms the skeleton of the body. It is composed chiefly of calcium phosphate and calcium carbonate . It also serves as a storage area for calcium, playing a large role in calcium balance in the blood.
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Bone density: Bone density is the amount of bone tissue in a certain volume of bone. It can be measured using a special x-ray called a quantitative computed tomogram.
Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively.
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Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Breast : The breast refers to the front of the chest or, more specifically, to the mammary gland. The mammary gland is a milk producing gland. It is composed largely of fat. Within the mammary gland is a complex network of branching ducts. These ducts exit from sac-like structures called lobules, which can produce milk in females. The ducts exit the breast at the nipple.
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Breast cancer: Breast cancer is diagnosed with self- and physician-examination of the breasts, mammography, ultrasound testing, and biopsy. There are many types of breast cancer that differ in their capability of spreading to other body tissues (metastasis). Treatment of breast cancer depends on the type and location of the breast cancer, as well as the age and health of the patient. The American Cancer Society recommends that a woman should have a baseline mammogram between the ages of 35 and 40 years. Between 40 and 50 years of age mammograms are recommended every other year. After age 50 years, yearly mammograms are recommended.
Burn: Damage to the skin or other body parts caused by extreme heat, flame, contact with heated objects, or chemicals. Burn depth is generally categorized as first, second, or third degree. The treatment of burns depends on the depth, area, and location of the burn, as well as additional factors, such as material that may be burned onto or into the skin. Treatment options range from simply applying a cold pack to emergency treatment to skin grafts.
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Bypass: An operation in which a surgeon creates a new tubular pathway for the movement of fluids and/or other substances in the body.
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Caffeine: A stimulant found naturally in coffee beans, tea leaves, cocoa beans (chocolate) and kola nuts (cola) and added to soft drinks, foods, and medicines. A cup of coffee has 100-250 milligrams of caffeine. Black tea brewed for 4 minutes has 40-100 milligrams. Green tea has one-third as much caffeine as black tea.
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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.
Calipers: A metal or plastic tool similar to a compass used to measure the diameter of an object. The skin fold thickness in several parts of the body can be measured with skin calipers to determine the lean body mass. This may be done in medicine, physical anthropology, health clubs, and athletic facilities.
Calorie: A unit of food energy. In nutrition terms, the word calorie is used instead of the more precise scientific term kilocalorie which represents the amount of energy required to raise the temperature of a liter of water one degree centigrade at sea level. The common usage of the word calorie of food energy is understood to refer to a kilocalorie and actually represents, therefore, 1000 true calories of energy. A calorie is also known as cal, gram calorie, or small calorie.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cancer of the rectum: See: Rectal cancer.
Capsule: Capsule has many meanings in medicine including the following: - In medicine, a membranous structure that envelops an organ, a joint, tumor, or any other part of the body. It is usually made up of dense collagen-containing connective tissue.
- In pharmacy, a solid dosage form in which the drug is enclosed in a hard or soft soluble container, usually of a form of gelatin.
- In microbiology, a coat around a microbe, such as a bacterium or fungus.
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Carbohydrate: Mainly sugars and starches, together constituting one of the three principal types of nutrients used as energy sources (calories) by the body. Carbohydrates can also be defined chemically as neutral compounds of carbon, hydrogen and oxygen.
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Carbohydrates: Mainly sugars and starches, together constituting one of the three principal types of nutrients used as energy sources (calories) by the body. Carbohydrates can also be defined chemically as neutral compounds of carbon, hydrogen and oxygen.
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Cerebrovascular: Pertaining to the blood vessels and, especially, the arteries that supply the brain. As in cerebrovascular accident or cerebrovascular disease.
Cerebrovascular accident: The sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A CVA is also referred to as a stroke .
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Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
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Childhood: (1) The time for a boy or girl from birth until he or she is an adult. (2) The more circumscribed period of time from infancy to the onset of puberty .
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Cholecystokinin: Abbreviated CCK. A polypeptide hormone that stimulates the contraction of the gallbladder with release of bile and the secretion of pancreatic enzymes into the small intestine. CCK is secreted by cells lining the upper intestine and by the hypothalamus. Hypothalamic cholecystokinin is a neurotransmitter. Called also pancreozymin.
Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Chronic disease: A disease that persists for a long time. A chronic disease is one lasting 3 months or more, by the definition of the U.S. National Center for Health Statistics. Chronic diseases generally cannot be prevented by vaccines or cured by medication, nor do they just disappear. Eighty-eight percent of Americans over 65 years of age have at least one chronic health condition (as of 1998). Health damaging behaviors - particularly tobacco use, lack of physical activity, and poor eating habits - are major contributors to the leading chronic diseases.
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Clinical: 1. Having to do with the examination and treatment of patients. 2. Applicable to patients. A laboratory test may be of clinical value (of use to patients).
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Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
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Colon: The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool , move through it to the rectum and leave the body through the anus . .
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Colon cancer: A malignancy that arises from the inner lining of the colon . Most, if not all, of these cancers develop from colonic polyps . Removal of these precancerous polyps can prevent colon cancer.
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Condition: The term "condition" has a number of biomedical meanings including the following: - An unhealthy state, such as in "this is a progressive condition."
- A state of fitness, such as "getting into condition."
- Something that is essential to the occurrence of something else; essentially a "precondition."
- As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.
Congestive heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
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Constipation: Infrequent (and frequently incomplete) bowel movements. The opposite of diarrhea, constipation is commonly caused by irritable bowel syndrome, diverticulosis, and medications (constipation can paradoxically be caused by overuse of laxatives). Colon cancer can narrow the colon and thereby cause constipation. The large bowel (colon) can be visualized by barium enema x-rays, sigmoidoscopy, and colonoscopy. Barring a condition such as cancer, high-fiber diets can frequently relieve the constipation.
Coronary artery disease: A major cause of illness and death, coronary artery disease (CAD) begins when hard cholesterol substances (plaques) are deposited within a coronary artery.
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Cream: A word with many meanings that, in medicine and pharmacy, refers to a water-soluble preparation applied to the skin. An ointment differs from a cream in that it has an oil base.
Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma .
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Cut: An area of severed skin. Wash a cut or scrape it with soap and water, and keep it clean and dry. Putting alcohol, hydrogen peroxide, or iodine into a wound can delay healing, and should be avoided. Seek medical care if you think you might need stitches, as delay can increase the rate of wound infection. If the cut results from a puncture wound through the shoe, there is a high risk of infection, and you should see your healthcare professional. Redness, swelling, increased pain, and pus draining from the wound also indicate an infection that requires professional care.
CVA: Cerebrovascular accident.
Degenerative arthritis: Also known as osteoarthritis, this type of arthritis is caused by inflammation, breakdown and eventual loss of the cartilage of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common, affecting usually the hands, feet, spine, and large weight-bearing joints, such as the hips and knees. Also called degenerative joint disease.
Dehydration : Excessive loss of body water. Diseases of the gastrointestinal tract that cause vomiting or diarrhea may, for example, lead to dehydration. There are a number of other causes of dehydration including heat exposure, prolonged vigorous exercise (e.g., in a marathon), kidney disease, and medications (diuretics).
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Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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DEXA: Dual energy X-ray absorptometry. See: DXA.
Dexfenfluramine: A weight loss drug, in a class of drugs called anorectics which decrease appetite. This drug, sold in the US under the brand name Redux, was withdrawn from the US market in 1997, and has since been withdrawn worldwide and is no longer available because of its association with abnormal heart valve findings, primarily aortic regurgitation.
Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diabetes mellitus: Better known just as " diabetes " -- a chronic disease associated with abnormally high levels of the sugar glucose in the blood. Diabetes is due to one of two mechanisms:
(1) Inadequate production of insulin (which is made by the pancreas and lowers blood glucose) or
(2) Inadequate sensitivity of cells to the action of insulin.
The two main types of diabetes correspond to these two mechanisms and are called insulin dependent (type 1) and non-insulin dependent (type 2) diabetes. In type 1 diabetes there is no insulin or not enough of it. In type 2 diabetes, there is generally enough insulin but the cells upon it should act are not normally sensitive to its action.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Dopamine: An important neurotransmitter (messenger) in the brain.
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Dry mouth: The condition of not having enough saliva to keep the mouth wet. This is due to inadequate function of the salivary glands. Everyone has dry mouth once in a while when they are nervous, upset or under stress. But if someone has a dry mouth most all of the time, it can be uncomfortable and lead to serious health problems.
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Egg: Ovum (plural: ova).
Endocrinology: The study of hormones , their receptors , the intracellular signalling pathways they invoke, and the diseases and conditions associated with them.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction .
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Epidemic: The occurrence of more cases of a disease than would be expected in a community or region during a given time period. A sudden severe outbreak of a disease such as SARS. From the Greek "epi-", "upon" + "demos", "people or population" = "epidemos" = "upon the population." See also: Endemic; Pandemic.
Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.
Essential: 1. Something that cannot be done without.
2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid.
3. Idiopathic. As in essential hypertension. "Essential" is a hallowed term meaning "We don't know the cause."
Estrogen: Estrogen is a female hormone produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Family: 1. A group of individuals related by blood or marriage or by a feeling of closeness. 2. A biological classification of related plants or animals that is a division below the order and above the genus. 3. A group of genes related in structure and in function that descended from an ancestral gene. 4. A group of gene products similarly related in structure and function and of shared genetic descent. 5. Parents and their children. The most fundamental social group in humans.
Fat: 1 Along with proteins and carbohydrates, one of the three nutrients used as energy sources by the body. The energy produced by fats is 9 calories per gram. Proteins and carbohydrates each provide 4 calories per gram. 2 Total fat; the sum of saturated, monounsaturated and polyunsaturated fats. Intake of monounsaturated and polyunsaturated fats can help reduce blood cholesterol when substituted for saturated fats in the diet. 3 A slang term for obese or adipose. 4 In chemistry, a compound formed from chemicals called fatty acids. These fats are greasy, solid materials found in animal tissues and in some plants. Fats are the major component of the flabby material of a body, commonly known as blubber.
Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Fats: Plural of the word "fat". See the definition of fat.
Fatty acid: One of many molecules that are long chains of lipid-carboxylic acid found in fats and oils and in cell membranes as a component of phospholipids and glycolipids. (Carboxylic acid is an organic acid containing the functional group -COOH.)
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Fatty acids: Molecules that are long chains of lipid-carboxylic acid found in fats and oils and in cell membranes as a component of phospholipids and glycolipids. (Carboxylic acid is an organic acid containing the functional group -COOH.)
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FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Fenfluramine: A weight loss drug, in a class of drugs called anorectics which decrease appetite. This drug, sold in the US under the brand name Pondimin, was withdrawn from the US market in 1997, and has since been withdrawn worldwide and is no longer available because of its association with abnormal heart valve findings, primarily aortic regurgitation.
Food and Drug Administration: The FDA, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Foot: The end of the leg on which a person normally stands and walks. The foot is an extremely complex anatomic structure made up of 26 bones and 33 joints that must work together with 19 muscles and 107 ligaments to execute highly precise movements. At the same time the foot must be strong to support more than 100,000 pounds of pressure for every mile walked. Even small changes in the foot can unexpectedly undermine its structural integrity and cause pain with every step.
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Forceps: An instrument with two blades and a handle used for handling, grasping, or compressing. Many types of forceps are employed in medicine, including the alligator forceps (an angled instrument with jaws at the end), tissue forceps (a form of tweezer), hemostatic forceps (also simply called a hemostat, to clamp a bleeding vessel), mosquito forceps (a small hemostat) and obstetrical forceps (to aid in delivering a baby).
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Fructose: A sugar that occurs naturally in fruits and honey. Fructose has 4 calories per gram.
Gallbladder: A pear-shaped organ just below the liver that stores the bile secreted by the liver. During a fatty meal, the gallbladder contracts, delivering the bile through the bile ducts into the intestines to help with digestion. Abnormal composition of bile leads to formation of gallstones, a process termed cholelithiasis. The gallstones cause cholecystitis, inflammation of the gallbladder.
Gallstones : Stones that form when substances in the bile harden. Gallstones can be as small as a grain of sand or as large as a golf ball. There can be just one large stone, hundreds of tiny stones, or any combination.
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Gastric: Having to do with the stomach.
Gastric banding: A surgically implanted device used to help a person lose weight. In a surgical procedure, a band is placed around the upper part of the stomach, creating a small pouch that can hold only a small amount of food. The narrowed opening between the stomach pouch and the rest of the stomach controls how quickly food passes from the pouch to the lower part of the stomach. The system helps the patient eat less by limiting the amount of food that can be eaten at one time and increasing the time it takes for food to be digested.
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Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
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Gastrointestinal tract: The tube that extends from the mouth to the anus in which the movement of muscles and release of hormones and enzymes digest food. The gastrointestinal tract starts with the mouth and proceeds to the esophagus, stomach, duodenum, small intestine, large intestine (colon), rectum and, finally, the anus. Also called the alimentary canal, digestive tract and, perhaps most often in conversation, the GI tract.
Genes: The basic biological units of heredity . Segments of deoxyribonucleic acid (DNA) needed to contribute to a function.
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Genetic: Having to do with genes and genetic information.
Genetic disease: A disease caused by an abnormality in an individual's genome .
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Genetics: The scientific study of heredity . Genetics pertains to humans and all other organisms. So, for example, there is human genetics, mouse genetics, fruitfly genetics, etc.
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Glucose: The simple sugar (monosaccharide) that serves as the chief source of energy in the body. Glucose is the principal sugar the body makes. The body makes glucose from proteins, fats and, in largest part, carbohydrates. Glucose is carried to each cell through the bloodstream. Cells, however, cannot use glucose without the help of insulin . Glucose is also known as dextrose.
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Gout: Condition characterized by abnormally elevated levels of uric acid in the blood, recurring attacks of joint inflammation (arthritis), deposits of hard lumps of uric acid in and around the joints, and decreased kidney function and kidney stones. Uric acid is a breakdown product of purines, that are part of many foods we eat. The tendency to develop gout and elevated blood uric acid level (hyperuricemia) is often inherited and can be promoted by obesity, weight gain, alcohol intake, high blood pressure, abnormal kidney function, and drugs. The most reliable diagnostic test for gout is the identification of crystals in joints, body fluids and tissues.
HDL: High density lipoprotein.
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HDL cholesterol: Lipoproteins, which are combinations of lipids (fats) and proteins, are the form in which lipids are transported in the blood. The high-density lipoproteins transport cholesterol from the tissues of the body to the liver so it can be gotten rid of (in the bile). HDL cholesterol is therefore considered the "good" cholesterol. The higher the HDL cholesterol level, the lower the risk of coronary artery disease.
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Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Health: As officially defined by the World Health Organization, a state of complete physical, mental, and social well-being, not merely the absence of disease or infirmity.
Health for All: A global health movement undertaken by the World Health Organization (WHO) in the late 20th century.
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart attack: The death of heart muscle due to the loss of blood supply. The loss of blood supply is usually caused by a complete blockage of a coronary artery, one of the arteries that supplies blood to the heart muscle. Death of the heart muscle, in turn, causes chest pain and electrical instability of the heart muscle tissue.
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Heart disease: Any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease. Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels. Among the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.
Heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
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Heart rate: The number of heart beats per unit time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast ( tachycardia ) or too slow ( bradycardia ). The pulse is bulge of an artery from the wave of blood coursing through the blood vessel as a result of the heart beat. The pulse is often taken at the wrist to estimate the heart rate.
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Heart valves: There are four heart valves. All are one-way valves. Blood entering the heart first passes through the tricuspid valve and then the pulmonary valve. After returning from the lungs, the blood passes through the mitral (bicuspid) valve and exits via the aortic valve.
Hemorrhagic: Pertaining to bleeding or the abnormal flow of blood.
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Herbal: 1. An adjective, referring to herbs, as in an herbal tea.
2. A noun, usually reflecting the botanical or medicinal aspects of herbs; also a book which catalogs and illustrates herbs.
The word "herbal" was pronounced with a silent "h" on both sides of the Atlantic until the 19th century but this usage persists only on the American side.
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High blood pressure : Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Hydrostatic weighing: See: Underwater weighing.
Hypercholesterolemia: High blood cholesterol. This can be sporadic (with no family history) or familial.
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Hypertension: High blood pressure , defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Hypothyroid: Deficiency of thyroid hormone which is normally made by the thyroid gland which is located in the front of the neck:
Incidence: The frequency with which something, such as a disease, appears in a particular population or area. In disease epidemiology, the incidence is the number of newly diagnosed cases during a specific time period. The incidence is distinct from the prevalence which refers to the number of cases alive on a certain date.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.
Insomnia: The perception or complaint of inadequate or poor-quality sleep because of one or more of the following: difficulty falling asleep; waking up frequently during the night with difficulty returning to sleep; waking up too early in the morning; or unrefreshing sleep. Insomnia is not defined by the number of hours of sleep a person gets or how long it takes to fall asleep. Individuals vary normally in their need for, and their satisfaction with, sleep. Insomnia may cause problems during the day, such as tiredness, a lack of energy, difficulty concentrating, and irritability.
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Insulin: A natural hormone made by the pancreas that controls the level of the sugar glucose in the blood. Insulin permits cells to use glucose for energy. Cells cannot utilize glucose without insulin.
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Insulin resistance: The diminished ability of cells to respond to the action of insulin in transporting glucose (sugar) from the bloodstream into muscle and other tissues. Insulin resistance typically develops with obesity and heralds the onset of type 2 diabetes. It is as if insulin is "knocking" on the door of muscle. The muscle hears the knock, opens up, and lets glucose in. But with insulin resistance, the muscle cannot hear the knocking of the insulin (the muscle is "resistant"). The pancreas makes more insulin, which increases insulin levels in the blood and causes a louder "knock." Eventually, the pancreas produces far more insulin than normal and the muscles continue to be resistant to the knock. As long as one can produce enough insulin to overcome this resistance, blood glucose levels remain normal. Once the pancreas is no longer able to keep up, blood glucose starts to rise, initially after meals, eventually even in the fasting state. Type 2 diabetes is now overt.
Iron: An essential mineral. Iron is necessary for the transport of oxygen (via hemoglobin in red blood cells) and for oxidation by cells (via cytochrome). Deficiency of iron is a common cause of anemia. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. Iron overload can damage the heart, liver, gonads and other organs. Iron overload is a particular risk in people who may have certain genetic conditions (hemochromatosis) sometimes without knowing it and also in people receiving recurrent blood transfusions. Iron supplements meant for adults (such as pregnant women) are a major cause of poisoning in children.
Journal of the American Medical Association: JAMA, which began publication in 1883, now bills itself as "the world's best-read medical journal". However one defines "best-read", JAMA clearly ranks as one of the two leading general medical journals published in the United States. The other is the New England Journal of Medicine.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.
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Large bowel: Another name for the large intestine .
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LDL cholesterol: Lipoproteins which are combinations of lipids (fats) and proteins are the form in which lipids are transported in the blood. The low-density lipoproteins transport cholesterol from the liver to the tissues of the body. LDL cholesterol is therefore considered the "bad" cholesterol.
Lean body mass: The mass of the body minus the fat (storage lipid). There are a number of methods for determining the lean body mass. Some of these methods require specialized equipment such as underwater weighing (hydrostatic weighing), BOD POD (a computerized chamber), and DEXA (dual-energy X-ray absorptiometry). Other methods for determining the lean body mass are simple such as skin calipers and bioelectric impedance analysis (BIA).
Leptin: A hormone that has a central role in fat metabolism. Leptin was originally thought to be a signal to lose weight but it may, instead, be a signal to the brain that there is fat on the body.
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.
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Lumen: A luminous term referring to the channel within a tube such as a blood vessel or to the cavity within a hollow organ such as the intestine . Lumen is a luminous term because it is Latin for light, including the light that comes through a window. When a hollow organ is cut across, you can see light through the space that has been opened. So the word "lumen" came to mean this space.
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Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.
Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")
Menopause : The time in a woman's life when menstrual periods permanently stop; it is also called the "change of life." Menopause is the opposite of the menarche.
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Metabolic: Relating to metabolism, the whole range of biochemical processes that occur within us (or any living organism). Metabolism consists of anabolism (the buildup of substances) and catabolism (the breakdown of substances).
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Metabolism: The whole range of biochemical processes that occur within us (or any living organism). Metabolism consists both of anabolism and catabolism (the buildup and breakdown of substances, respectively). The term is commonly used to refer specifically to the breakdown of food and its transformation into energy.
Mind: That which thinks, reasons, perceives, wills, and feels. The mind now appears in no way separate from the brain. In neuroscience, there is no duality between the mind and body. They are one.
Mortality: A fatal outcome or, in one word, death. The word "mortality" is derived from "mortal" which came from the Latin "mors" (death). The opposite of mortality is, of course, immortality. Mortality is also quite distinct from morbidity (illness).
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Muscular: Having to do with the muscles. Also, endowed with above average muscle development. Muscular system refers to all of the muscles of the body collectively.
Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.
NIH: The National Institutes of Health. The NIH is an important U.S. health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate Institutes and Centers. NIH's program activities are represented by these Institutes and Centers.
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Normal range: By convention, the normal range for whatever (a particular test, condition, symptom, behavior, etc.) is set to cover ninety-five percent (95%) of all values from the general population. Five percent (5%) of results consequently fall outside the normal range. Values that prove normal can therefore sometimes be outside the normal range.
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Nurses Health Study: A very large and important prospective investigation into the risk factors for major chronic diseases in women. (In a prospective study the participants are identified and then followed forward in time.) The participants in the study are female registered nurses (RNs).
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Nutrition : 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.
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Obese: Well above ones normal weight. A person has traditionally been considered to be obese if they are more than 20 percent over their ideal weight. That ideal weight must take into account the person's height, age, sex, and build.
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Obesity: The state of being well above one's normal weight.
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Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Osteoarthritis: A type of arthritis caused by inflammation, breakdown, and eventual loss of cartilage in the joints. Also known as degenerative arthritis.
Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Ovary: The female gonad, the ovary is one of a pair of reproductive glands in women. They are located in the pelvis, one on each side of the uterus. Each ovary is about the size and shape of an almond. The ovaries produce eggs (ova) and female hormones. During each monthly menstrual cycle, an egg is released from one ovary. The egg travels from the ovary through a fallopian tube to the uterus. The ovaries are the main source of female hormones, which control the development of female body characteristics, such as the breasts, body shape, and body hair. They also regulate the menstrual cycle and pregnancy.
Overweight: The term "overweight" is used in two different ways. In one sense it is a way of saying imprecisely that someone is heavy. The other sense of "overweight" is more precise and designates a state between normal weight and obesity .
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pancreas: A fish-shaped spongy grayish-pink organ about 6 inches (15 cm) long that stretches across the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen and is connected to the duodenum (the first section of the small intestine). The narrow end of the pancreas, called the tail, extends to the left side of the body.
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Peptide: A molecule consisting of 2 or more amino acids. Peptides are smaller than proteins, which are also chains of amino acids. Molecules small enough to be synthesized from the constituent amino acids are, by convention, called peptides rather than proteins. The dividing line is at about 50 amino acids. Depending on the number of amino acids, peptides are called dipeptides, tripeptides, tetrapeptides, and so on.
Phenylalanine: An essential amino acid . (The human body cannot make it so it is essential to the diet.) Phenylalanine that is ingested is largely transformed (hydroxylated) to form the amino acid tyrosine, which is used in protein synthesis . Too little phenylalanine curbs physical and intellectual growth. Too much phenylalanine, as in phenylketonuria ( PKU ), is highly toxic to the brain. Phenylanine was first isolated in 1879 and first synthesized in 1882. Symbol: Phe.
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Phenylketonuria : The inherited inability to metabolize (process) the essential amino acid phenylalanine due to complete or near-complete deficiency of the enzyme phenylalanine hydroxylase.
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Physiologic: Something that is normal, neither due to anything pathologic nor significant in terms of causing illness.
Pickwickian syndrome: The combination of obesity, somnolence (sleepiness), hypoventilation (underbreathing), and plethoric (red) face.
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Pill: In pharmacy, a medicinal substance in a small round or oval mass meant to be swallowed. Pills often contain a filler and a plastic substance such as lactose that permits the pill to be rolled by hand or machine into the desired form. The pill may then be coated with a varnishlike substance.
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Placebo: A "sugar pill" or any dummy medication or treatment.
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Placenta: A temporary organ joining the mother and fetus, the placenta transfers oxygen and nutrients from the mother to the fetus, and permits the release of carbon dioxide and waste products from the fetus. It is roughly disk-shaped, and at full term measures about seven inches in diameter and a bit less than two inches thick. The upper surface of the placenta is smooth, while the under surface is rough. The placenta is rich in blood vessels.
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Polycystic ovary syndrome: Abbreviated PCOS. A condition of women characterized by irregular or no menstrual periods, acne , obesity , and excess hair growth. PCOS is a disorder of chronically abnormal ovarian function and hyperandrogenism (abnormally elevated androgen levels). It affects 5-10% of women of reproductive age. PCOS is also called the Stein-Leventhal syndrome.
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Postmenopausal: After the menopause . Postmenopausal is defined formally as the time after which a woman has experienced twelve (12) consecutive months of amenorrhea (lack of menstruation) without a period.
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Potassium: The major positive ion (cation) found inside of cells. The chemical notation for potassium is K+.
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Pound: A measure of weight equal to 16 ounces or, metrically, 453.6 grams. The word "pound" goes back to the Latin "pondo" which meant a "weight" (but one of only 12 ounces). The abbreviation for pound-just to confuse non-pound people-is lb. which stands for "libra" (Latin for pound).
Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pregnant: The state of carrying a developing fetus within the body.
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Prostate: A gland within the male reproductive system that is located just below the bladder. Chestnut shaped, the prostate surrounds the beginning of the urethra, the canal that empties the bladder.
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Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Proteins: Large molecules composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Public health: The approach to medicine that is concerned with the health of the community as a whole. Public health is community health. It has been said that: "Health care is vital to all of us some of the time, but public health is vital to all of us all of the time."
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Pulmonary: Having to do with the lungs. (The word comes from the Latin pulmo for lung).
Pulmonary hypertension : High blood pressure in the pulmonary artery that conveys blood from the right ventricle to the lungs. The pressure in the pulmonary artery is normally low compared to that in the aorta . Pulmonary hypertension can irrevocably damage the lungs and cause failure of the right ventricle.
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Race: An ethnic stock or division of humans. Naturalists and ethnographers have long divided humans into a variable number of distinct races. However, DNA and other genetic studies have revealed that that most genetic variation, about 94%, is within so-called racial groups while these racial groupings differ from one another only in about 6% of their genes. This means that there is greater genetic variation within racial groups than between them. The concept of race is a superficial and subjective one. All of humankind is a single species.
Randomized: The use of chance alone to assign the participants in an experiment or trial to different groups in order to fairly compare the outcomes with different treatments. Randomization is an important feature of experimental design.
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Range: In medicine and statistics, the difference between the lowest and highest numerical values. For example, if five premature infants are born weighing two, three, four, four, and five pounds respectively, the range of their birth weights is two to five pounds.
Re-uptake: See: Reuptake.
Rectum: The last 6 to 8 inches of the large intestine. The rectum stores solid waste until it leaves the body through the anus. The word rectum comes from the Latin rectus meaning straight (which the human rectum is not).
Redux: See: Dexfenfluramine.
Relapse: The return of signs and symptoms of a disease after a patient has enjoyed a remission . For example, after treatment a patient with cancer of the colon went into remission with no sign or symptom of the tumor, remained in remission for 4 years, but then suffered a relapse and had to be treated once again for colon cancer.
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Resistance: Opposition to something, or the ability to withstand it. For example, some forms of staphylococcus are resistant to treatment with antibiotics.
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Saccharin: An artificial sweetener which diluted in water is 300-500 times sweeter than the sugar sucrose. (Saccharin is o-sulfobenzimide; 2,3-dihydro-3-oxobenzisosulfonazole.)
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Salt: In medicine, salt usually refers to sodium chloride, table salt, used for seasoning food, for the preservation of meat, etc. Salt is found in the earth and in sea water and is isolated by evaporation and crystallization from sea water and other water impregnated with particles of salt.
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Saturated fat: A fat that is solid at room temperature and comes chiefly from animal food products. Some examples are butter, lard, meat fat, solid shortening, palm oil, and coconut oil. These fats tend to raise the level of cholesterol in the blood.
Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
Serotonin: A hormone , also called 5-hydroxytryptamine , in the pineal gland , blood platelets, the digestive tract, and the brain. Serotonin acts both as a chemical messenger that transmits nerve signals between nerve cells and that causes blood vessels to narrow.
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Side effects: Problems that occur when treatment goes beyond the desired effect. Or problems that occur in addition to the desired therapeutic effect.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.
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Skin calipers: A simple method for determining the lean body mass. This method involves measuring the skinfold thickness of the layer of fat just under the skin in several parts of the body with calipers. The results are then calculated and the percentage of body fat is determined. Skin calipers can yield inaccurate results if an inexperienced person uses them on someone with significant obesity.
Sleep : The body's rest cycle.
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Sleep apnea: The temporary stoppage of breathing during sleep , often resulting in daytime sleepiness. Apnea is a Greek word that means "want of breath."
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Small bowel: Another name for the small intestine .
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Sodium: The major positive ion (cation) in fluid outside of cells. The chemical notation for sodium is Na+. When combined with chloride, the resulting substance is table salt.
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Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Strain: 1. An injury to a tendon or muscle resulting from overuse or trauma. 2. A hereditary tendency that originated from a common ancestor. 3. To exert maximum effort. 4. To filter.
Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
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Stroke : The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
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Superior: In antomy, above or over top of. As opposed to inferior. The heart is superior to the stomach. The superior surface of the tongue rests against the palate.
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Sympathetic nervous system: A part of the nervous system that serves to accelerate the heart rate, constrict blood vessels, and raise blood pressure. The sympathetic nervous system and the parasympathetic nervous system constitute the autonomic nervous system, the branch of the nervous system that performs involuntary functions.
Synapse: The point of connection usually between two nerve cells. Specifically, a synapse is a specialized junction at which a nerve cell (a neuron ) communicates with a target cell. The neuron releases a chemical transmitter (a neurotransmitter ) that diffuses across a small gap and activates specific specialized sites called receptors situated on the target cell. The target cell may be another neuron, or a specialized region of a muscle cell or a secretory cell (a cell than can make and secrete a substance). Neurons can also communicate through direct electrical connections (electrical synapses).
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Synthesis: Putting together different entities to make a whole which is new and different. In biochemistry , synthesis refers specifically to the process of building compounds from more elementary substances by means of one or more chemical reactions.
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Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.
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Taste: Taste belongs to our chemical sensing system, or the chemosenses. The complicated process of tasting begins when molecules released by the substances stimulate special cells in the mouth or throat. These special sensory cells transmit messages through nerves to the brain where specific tastes are identified.
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Temperature: The temperature is the specific degree of hotness or coldness of the body. It is usually measured with a thermometer.
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Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus, - The bone marrow is a tissue;
- Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
- Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.
Treadmill: A machine with a moving strip on which one walks without moving forward. A treadmill was originally a wide wheel turned by the weight of people climbing on steps around its edge, used in the past to provide power for machines or as a punishment in prisons.
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Twin: One of two children produced in the same pregnancy and born during the same birth process.
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Type 2 diabetes: See Diabetes, type 2.
Underventilation: See: Hypoventilation.
Underwater weighing: A method for determining the lean body mass. This method weighs a person underwater and then calculates the lean body mass (muscle) and body fat. This method is one of the more accurate ones. However, it is generally done in special research facilities, and the equipment is costly. Also called hydrostatic weighing.
Uterus: The uterus (womb) is a hollow, pear-shaped organ located in a woman's lower abdomen between the bladder and the rectum. The narrow, lower portion of the uterus is the cervix; the broader, upper part is the corpus. The corpus is made up of two layers of tissue.
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Vitamins: The word "vitamin" was coined in 1911 by the Warsaw-born biochemist Casimir Funk (1884-1967). At the Lister Institute in London, Funk isolated a substance that prevented nerve inflammation (neuritis) in chickens raised on a diet deficient in that substance. He named the substance "vitamine" because he believed it was necessary to life and it was a chemical amine. The "e" at the end was later removed when it was recognized that vitamins need not be amines.
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Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).
Wrist: The proximal segment (the near part) of the hand consisting of the carpal bones and the associated soft parts.
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X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.
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Xylitol : A sweetener found in plants that is used as a substitute for sugar. Xylitol is considered a nutritive sweetener because it provides calories, just like sugar. ( Saccharin is an example of a nonnutritive sweetener, one that has no calories.)
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- Tummy Tuck ( Abdominoplasty) - Abdominoplasty, (tummy tuck) is one of the more common cosmetic surgeries. This procedure flattens your abdomen by removing extra fat and skin, and tightening muscles in your abdominal wall. Source:WebMD Medical Reference from The Cleveland Clinic
- C-Reactive Protein Test (CRP) - Learn about your heart disease risk and how the CRP test can be a marker of the inflammation of arteries. Source:WebMD Medical Reference from The Cleveland Clinic
- Liposuction - liposuction involves the surgical suctioning of fat deposits from specific parts of the body, the most common being the abdomen (the "tummy"), buttocks ("behind"), hips, and thighs. Source:WebMD Medical Reference from The Cleveland Clinic
- Read 1112 more Obesity (Weight Loss) related articles ...
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